San Francisco 49ers at Indianapolis Colts | Cael Sports

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Last updated Tue, Nov 10, 3:02 PM EST

San Francisco 49ers at Indianapolis Colts | Cael Sports

NFL · 2025 · Week 16

49ersSan Francisco 49ersAway

48 – 27Final

ColtsIndianapolis ColtsHome

Mon, Dec 22, 8:15 PM EST · Lucas Oil Stadium

Team	Q1	Q2	Q3	Q4	T
SF	14	10	10	14	48
IND	7	10	3	7	27